Deficiency in DNA damage response, a new characteristic of cells infected with latent HIV-1
نویسندگان
چکیده
منابع مشابه
Deficiency in DNA damage response, a new characteristic of cells infected with latent HIV-1.
Viruses can interact with host cell molecules responsible for the recognition and repair of DNA lesions, resulting in dysfunctional DNA damage response (DDR). Cells with inefficient DDR are more vulnerable to therapeutic approaches that target DDR, thereby raising DNA damage to a threshold that triggers apoptosis. Here, we demonstrate that 2 Jurkat-derived cell lines with incorporated silent HI...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2017
ISSN: 1538-4101,1551-4005
DOI: 10.1080/15384101.2017.1312225